Artistic depiction of seizure activity on EEG over watercolor brush strokes

Epilepsy

Epilepsy

The fourth most common neurological disorder is epilepsy, characterized by spontaneous and recurring seizures. Roughly, 65 million people world-wide are living with epilepsy, including 3.5 million individuals in the U.S., 500,000 of whom are children. Epilepsy can occur anytime in a person’s life, and 1 in 26 people will have epilepsy during their lifetime.  While seizures are the primary hallmark of epilepsy, over 1/3 of patients experience a spectrum of co-morbidities that can include altered cognitive development, as well as deficits in learning and memory, mood disorders and depression. There are still many unknowns about epilepsy, including how and why epileptic networks form and what are the cellular and molecular underpinnings of epilepsy. Moreover, a significant population of patients with epilepsy are resistant to medical intervention. UC Davis has a team of neuroscientists and clinician scientists who are dedicated to studying epilepsy and developing novel therapies for epilepsy. We also have a strong group of translational neuroscientist entrepreneurs who are developing new treatments and leading clinical trials at the cutting-edge of clinical care. 28 faculty members from 8 departments and 5 centers work in this area.

Faculty studying epilepsy

 

William Benko, M.D.  Neurodegenerative conditions; epilepsy and pediatric neurology
Amy R. Brooks-Kayal, M.D., F.A.A.N., F.A.N.A., F.A.E.S. Pediatric epilepsy
Michelle Chan, Ph.D. Neuropsychology; dementia; movement disorders and epilepsy
Celia H. Chang, M.D. Inpatient care, epilepsy and genetic conditions
Marco Gonzalez, Ph.D. Cellular and molecular alterations during epileptogenesis and epilepsy
Gene Gurkoff, Ph.D. Developing therapies to improve neural connectivity for patients with neurological disease
Trishna Kantamneni, M.D. Pediatric epilepsy; pediatric neurology
Kiran M. Kanth, M.D.  Neurology; epilepsy; neurophysiology
Jeffrey Kennedy, M.D. Epilepsy
Pamela J. Lein, Ph.D. Impacts of environmental stressors on the developing and aging brain
Shannon N. Liang, M.D. Pediatric neurology
Karen Moxon, Ph.D.  Neural encoding and plasticity, neuroprosthetics, neuroengineering, brain-machine interfaces
Alex Nord, Ph.D. Genomics in the brain development, function, and disorders 
Temitayo Oyegbile-Chidi M.D., Ph.D. Epilepsy and sleep disorders in children and young adults
Palak D. Parikh, M.D. Epilepsy
Katherine Park, M.D.  Epilepsy
Isaac Pessah, Ph.D. Molecular and cellular mechanisms regulating ryanodine receptors and Ca2+ signaling
Charan Ranganath, Ph.D. Neural basis and functional organization of human learning and memory
Michael A. Rogawski, M.D., Ph.D. Cellular and synaptic neurophysiology; neurosteroids; epilepsy and migraine; drug development.
Erkin Seker, Ph.D. Multifunctional electrodes; nucleic acid sensors; microfluidic tissue models
Masud Seyal, M.D., Ph.D. General neurology, epilepsy
Kia Shahlaie, M.D., Ph.D. Deep brain stimulation techniques to improve learning and memory function; traumatic brain injury, epilepsy, Parkinson's disease
Julia Devi Sharma, M.D., F.R.C.S.C, F.A.A.N.S. Surgical treatment of epilepsy; technical optimization of SEEG and intracranial recordings to study cognition
Jill L. Silverman, Ph.D. Curative, precision strategies for single gene caused neurodevelopmental disorders (NDDs), intellectual disabilities and pediatric epilepsies
Jeffrey Vitt, M.D.  Neurocritical care
Craig Watson, M.D., Ph.D. Epilepsy; neuroanatomy
Andrew Yonelinas, Ph.D.  Memory, perception and amnesia